Can you have too many colors?

We'll get back to talking pencils in due course but I'd like to bring a bit of color into the mix. About a year ago I took a chance on a set of color pens I'd never heard of before. "100 Unique Fineliners" by Shuttle Art. Unfortunately, real life has kept me from using them until very recently, but I've finally had a chance to take some of them out for a test drive.